Fast desensitization is an important regulatory mechanism of neuronal NMDA receptor function. Only recombinant NMDA receptors composed of NR1/NR2A exhibit a fast component of desensitization similar ...

In a milestone for protein engineering, researchers have designed from scratch a protein that exhibits allosteric regulation. With allostery, binding at one site of a protein affects binding or ...

Ras dimerization is critical for Raf activation. Here we show that the Ras binding domain of Raf (Raf-RBD) induces robust Ras dimerization at low surface densities on supported lipid bilayers and, to ...

DT-9045 is a game-changer in immuno-oncology with competitive pharmacological properties and unique therapeutic potential to unlock new cancer treatment possibilities - Preclinical studies highlight ...

Researchers have published research results this week that show how methicillin-resistant Staphylococcus aureus (MRSA) regulates the critical crosslinking of its cell wall in the face of beta-lactam ...

SHANGHAI, May 17, 2017 /PRNewswire/ -- A team of scientists led by the iHuman Institute of ShanghaiTech University in collaboration with Fudan University has determined the high-resolution crystal ...

New study conducted by scientists shows how MRSA regulates the critical crosslinking of its cell wall in the face of beta-lactam antibiotics. Modern strains of MRSA have become broadly resistant to ...

University of Notre Dame researchers Shahriar Mobashery and Mayland Chang and their collaborators in Spain have published research results this week that show how methicillin-resistant Staphylococcus ...