The invention that first enabled researchers to see clear images of living cells was the phase-contrast microscope, which won its inventor, Frits Zernike, a Nobel Prize in 1932. Prior to Zernike's ...

To carry out their study, the team developed an orientation-independent-differential interference contrast (OI-DIC) microscopy system combined with a confocal laser scanning microscope capable of ...

Light microscopy is a key tool that scientists use to image cells, organelles, subcellular structures, and molecules such as proteins and nucleic acids. Because visible light leaves biological ...

All around us, a hidden world exists that remains invisible to the naked eye. The adult human body has between 28 and 36 trillion cells spread over 400 cell types, all too small to be seen, except for ...

The use of high-resolution bright-field microscopy is essential for cellular-scale biological research, but this technique has limitations due to low image contrast. Using dyes on the sample can ...