Objective—Use of gastric bypass surgery is common and increasing. Over 40% of patients in diabetes remission after gastric bypass surgery may redevelop diabetes within 5 years. Metformin, the ...

Prodrugs are bioreversible derivatives of drug molecules that must undergo an enzymatic and/or chemical transformation in vivo to release the active parent drug, which can then exert its desired ...

Few natural products have demonstrated the range of protective and therapeutic promise as have turmeric and its principal bioactive components, the curcuminoids. Success in translating this potential ...

The potential for adverse systemic health effects resulting from dermal contact with a chemical is broadly recognized. In situations where dermal contact may contribute significantly to the total body ...

Chondroitin sulfate is a heterogeneous polysaccharide in terms of structure, molecular mass, and biological and pharmacological properties. The structure and properties of polysaccharides strongly ...

Model-based formulation and technology selection methodologies facilitate rapid product development. A large percentage of new chemical entities (NCEs) have physicochemical properties that require ...