This Collection supports and amplifies research related to SDG 3: Good Health & Wellbeing. The human genome is a vast landscape, with less than 2% of its sequence encoding proteins. For many years, ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too ...

Non-coding RNAs and oxidative stress work together in various stages of cancer progression, including cancer cell growth and reproduction, cancer cell invasion, tumor microenvironment shaping, ...

The study shows that a long non-coding RNA called CISTR-ACT acts as a master regulator of cell size, influencing how large or ...

Chinese Medical Journals Publishing House Co., Ltd. Pancreatic cancer, one of the leading causes of deaths, refers to the abnormal growth of cells in the pancreas. Only 10% of patients live more than ...

Researchers have successfully employed an algorithm to identify potential mutations which increase disease risk in the noncoding regions our DNA, which make up the vast majority of the human genome.

Originally classified as ‘junk DNA’, genomic regions which are transcribed into RNAs that do not serve as template for protein production have attracted increasing attention in the last two decades.

The expression of genes has to be very carefully controlled by cells; serious problems can arise when genes are expressed in the wrong places, at the wrong times, or at the wrong levels, for some ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are ...

A tiny percentage of our DNA—around 2%—contains 20,000-odd genes. The remaining 98%—long known as the non-coding genome, or ...

The enigmatic facial morphology of our Neanderthal cousins, characterized by a robust and prominent jaw, finds part of its explanation in the least known areas of our genetic heritage. A team from the ...