The genome is more than a linear code; it is a dynamic structure whose three-dimensional folding dictates how genes are regulated. Traditional sequencing technologies capture base-level variation but ...

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

DNA isn't just a long string of genetic code, but an intricate 3D structure folded inside each cell. That means the tools used to study DNA need to be just as sophisticated-able to read not only the ...

Imagine if you could "print" a tiny skyscraper using DNA instead of steel. That’s what researchers at Columbia and Brookhaven are doing—constructing intricate 3D nanostructures by harnessing the ...

Chip-integrated 3D nanostructured device fabricated using DNA self-assembly (Left panel). A DNA crystal is grown at a designated substrate location (about 1000 crystals on 5μm pads are shown on a ...