On immune cells, Toll-like receptors are capable of detecting infections just like a sniffer dog, using special sensors known as Toll-like receptors, or TLRs for short. But what signals activate TLRs, ...

Researchers have discovered that the interferon gamma receptor (IFNgR) signaling pathway is critical for susceptibility of glioblastoma tumors to killing by CAR T-cell immunotherapy. Researchers at ...

Toll-like receptors, or TLRs, are the immune system’s early warning sensors. They detect microbial invaders and damage signals, helping the body mount a defense. But when TLR signaling veers off ...