Among adults treated for community-acquired pneumonia in the outpatient setting, broad-spectrum antibiotics vs macrolide monotherapy were associated with an increased risk for adverse drug events.

Clinical outcomes among adult inpatients were no worse when broad-spectrum antibiotic therapy was delayed vs started early, challenging the belief that overly broad-spectrum empiric antibiotic therapy ...

An international research team found some beneficial bacteria in people’s guts may not return after broad-spectrum antibiotic exposure, according to a study published in Nature Microbiology. 1.

Despite growing awareness of the development of antibiotic resistance and support for stewardship programs, the overall rate of antibiotic use in the U.S. didn’t change from 2006 to 2012, and there ...

Bacteria have long been a key source of lifesaving antibiotics, but most species cannot be grown in the lab—leaving their therapeutic potential untapped even as multidrug resistance becomes an ...

Broad-spectrum antibiotics are used more generally when the organism is unknown, exacerbating AMR. The UK government report, published in 2016, recommended testing for pathogens before prescribing and ...

About half of suspected sepsis cases account for broad-spectrum antibiotic use — but a lot of these cases don’t require the medications at all, according to a study published June 27 in JAMA Network ...

Pneumonia and urinary tract infections are the two most common infections requiring hospitalizations and major reasons for the overuse of broad-spectrum antibiotics. While UTIs require 480,000 ...

The Pediatric Infectious Diseases Society and the Infectious Diseases Society of America published a guideline in 2011 detailing recommended treatment for children with community-acquired pneumonia ...

Three years ago, Yale University professor of molecular biophysics and biochemistry Thomas Steitz won the Nobel Prize in chemistry for his research on the structure and function of the ribosome. Now, ...