Biology-inspired brain model matches animal learning and reveals overlooked neuron activity

A new computational model of the brain based closely on its biology and physiology has not only learned a simple visual ...

Kanazawa University research: High-speed AFM imaging reveals how brain enzyme forms dodecameric ring structure

Scientists at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have captured real-time images showing how a key brain ...
Frontiers

Machine learning-assisted network pharmacology reveals that the Chaihu-Longgu-Muli decoction modulates the inflammatory microenvironment to treat perimenopausal syndrome

Background: Chaihu-Longgu-Muli decoction (CLMD) is a traditional Chinese medicine formula that shows promise in alleviating symptoms related to premenstrual syndrome (PMS). However, the underlying ...
eLife

Ω-Loop mutations control dynamics of the active site by modulating the hydrogen-bonding network in PDC-3 β-lactamase

This manuscript uses simulations to describe the dynamics of the Pseudomonas-derived cephalosporinase PDC-3 β-lactamase and its mutants to better understand antibiotic resistance. The finding that ...
Frontiers

Screening and experimental validation of modified Gandou Decoction-targeted inhibitors for alleviating AD components via network pharmacology, machine learning, and molecular ...

Background: Alzheimer’s disease (AD) is a neurodegenerative disease characterized by abnormal accumulation of β-amyloid (Aβ) and hyperphosphorylation of the Tau protein. Currently, there is a lack of ...
U.S. News & World Report

iShares Dynamic Equity Active ETF

Learn everything you need to know about iShares Dynamic Equity Active ETF (BDYN) and how it ranks compared to other funds. Research performance, expense ratio, holdings, and volatility to see if it's ...
IEEE

Dynamic Confidence Variance for Generalized Coreset in Active Learning

Abstract: Active Learning (AL) aims to reduce data annotation costs by selecting the most informative samples from an unlabeled data pool. Traditional AL methods often rely on a single snapshot to ...
C&EN

Integrating Machine Learning into Free Energy Perturbation Workflows

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Free energy perturbation (FEP) methods are among the most accurate tools in ...
C&EN

Reactive Active Learning: An Efficient Approach for Training Machine Learning Interatomic Potentials for Reacting Systems

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Discovering chemical reaction pathways using quantum mechanics is impractical for many ...
Microsoft

Use least active routing on messaging channels

In customer service, efficient workload distribution is vital for high customer satisfaction and operational efficiency. Unified routing capabilities in Dynamics 365 Customer Service and Dynamics 365 ...